World's Largest Cancer Database, the US-based SEER program sets world record

June 6, 2025

Bethesda, Maryland, United States--The Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute (NCI) is a source of epidemiologic information on the incidence and survival rates of cancer in the United States; IT is a clinically-based database containing approximately 40 million records and it is considered the world's largest cancer database, according to the WORLD RECORD ACADEMY.

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"The US-based SEER program (Surveillance, Epidemiology, and End Results) is considered the world's largest cancer database. It is managed by the National Cancer Institute (NCI) and provides comprehensive data on cancer incidence, mortality, and survival rates in the US.

"Additionally, the National Cancer Database (NCDB) is a clinically-based database containing approximately 40 million records. The CanSAR database is another significant resource for cancer research, focusing on drug discovery.

"The Cancer Genome Atlas (TCGA) is a landmark cancer genomics program that has molecularly characterized over 20,000 primary cancer samples and matched normal samples across 33 cancer types." (Google/AI Overview)

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"The Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute (NCI) is an authoritative source of information on cancer incidence and survival in the United States. SEER currently collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 45.9 percent of the U.S. population. For more information on this, please view the SEER Research Data," the SEER Program says.

"SEER coverage includes 39.6 percent of Whites, 43.5 percent of African Americans, 64.9 percent of Hispanics, 59.3 percent of American Indians and Alaska Natives, 68.2 percent of Asians, and 69.9 percent of Hawaiian/Pacific Islanders. (Details are provided in the table: Number of Persons by Race and Hispanic Ethnicity for SEER Participants.)

"The SEER Program registries routinely collect data on patient demographics, primary tumor site, tumor morphology and stage at diagnosis, first course of treatment, and follow-up for vital status. The SEER Program is the only comprehensive source of population-based information in the United States that includes stage of cancer at the time of diagnosis and patient survival data. The mortality data reported by SEER are provided by the National Center for Health Statistics."

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"The population data used in calculating cancer rates is obtained periodically from the Census Bureau. Updated annually and provided as a public service in print and electronic formats, SEER data are used by thousands of researchers, clinicians, public health officials, legislators, policymakers, community groups, and the public," the SEER Program says.

"NCI staff work with the North American Association of Central Cancer Registries (NAACCR)External Web Site Policy to guide all state registries to achieve data content and compatibility acceptable for pooling data and improving national estimates.

"The SEER team is developing computer applications to unify cancer registration systems and to analyze and disseminate population-based data. Use of surveillance data for research is being improved through Web-based access to the data and analytic tools, and linking with other national data sources."

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"The Surveillance, Epidemiology, and End Results Program (SEER) tracks the incidence of persons diagnosed with cancer during the year and collects follow-up information on all previously diagnosed patients until their death," the health.gov says.

"Participating sites include: (1) twelve states with central cancer registries: Connecticut, Georgia, Hawaii, Idaho, Iowa, Kentucky, Louisiana, Massachusetts, New Jersey, New Mexico, New York, and Utah; and (2) four metropolitan, multi-county areas: (Greater California, Los Angeles, and Greater Bay Area -- San Francisco/Oakland, San Jose/Monterey); (Atlanta, Greater Georgia, and Rural Georgia); Seattle-Puget Sound; and Detroit. Metro areas are combined for data to complete states for CA and GA.

"SEER registries that report data are upheld to data standards as part of the North American Association of Central Cancer Registries (NAACCR). The completeness standard for malignant primary tumors is 98 percent or greater."

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"The Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute (NCI) is a source of epidemiologic information on the incidence and survival rates of cancer in the United States.

"SEER collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 45.9% of the population of the United States. SEER coverage includes 39.6% of Whites, 43.5% of African Americans, 64.9% of Hispanics, 59.3% of American Indians and Alaska Natives, 68.2% of Asians, and 69.9% of Hawaiian/Pacific Islanders.